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Hexamethonium bromide (C15-1248-578)

Catalog No.
C15-1248-578
Manufacturer No.
H0879-25G
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
GR
Price: $198.64
List Price: $220.71

Application Hexamethonium bromide has been used: as an autonomic ganglia-blocking agent to study its effects on whisker movement in rats as a nicotinic receptor antagonist to study its effects on antigen-induced arthritis (AIA) progression in mice

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Application

Hexamethonium bromide has been used:

  • as an autonomic ganglia-blocking agent to study its effects on whisker movement in rats
  • as a nicotinic receptor antagonist to study its effects on antigen-induced arthritis (AIA) progression in mice
  • as a non-selective ganglionic nicotinic acetylcholine receptor (nAChR) antagonist to study its effects on cytisine-induced autonomic cardiovascular responses in mice

Biochem/physiol Actions

Hexamethonium bromide is a nicotinic acetylcholine receptor (nAChR) antagonist. It preferentially blocks nicotinic receptors at autonomic ganglia. It can cross the blood-brain barrier only at high doses.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:
51434107
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
H0879-25G


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