HPLC column (analytical), NUCLEOSIL 100-5 C8, length: 125 mm, ID: 4.6mm, USP: L7, 1 Column

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure Wide acceptance as routine packings for very different fields of chromatography One of the first spherical silicas used in HPLC Developed in the early seventies, it became a world-renowned HPLC packing Still found in many analytical and preparative application An absolutely reliable choice in HPLC The largest variety of modified HPLC silicas available on the market NUCLEOSIL® C8 ec: Endcapped, pore size 100 Å, particle size 5 µm Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions Corresponding HPLC phase based on NUCLEODUR® high purity silica: NUCLEODUR® C8 ec Carbon content 9 % NUCLEOSIL® C8: Not endcapped, available pore sizes 100, 120, and 300 Å Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm Separation mechanism based on hydrophobic (van der Waals) interactions, noticeable silanol interactions pH stability at 20 °C: 2–8 Carbon content depends on pore size ~3 % (300 Å) up to 8.5 % (100 Å) Features Octyl modified silica phases for HPLC, USP L7 Nonpolar phases for RP chromatography C8 ec: medium density modification, endcapped C8: not encapped Recommended application General RP application in HPLC; shows lower retention than C18 phases