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Human MIP-4/PARC (CCL18), 10ug

Catalog No.
C08-0302-310
Manufacturer No.
RC315-29.SIZE.10ug
Manufacturer Name
Bio Basic Inc
Quantity
1
Unit of Measure
EA
Price: $262.32
List Price: $291.47

MIP-4, PARC, CCL18, human: CCL18, is a novel CC chemokine that is highly homologous to MIP-1&alpha (61% amino acid sequence identity). CCL18 cDNA encodes an 89 aa residue precursor protein with a 20 aa putative signal peptide that is cleaved to

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MIP-4, PARC, CCL18, human: CCL18, is a novel CC chemokine that is highly homologous to MIP-1α (61% amino acid sequence identity). CCL18 cDNA encodes an 89 aa residue precursor protein with a 20 aa putative signal peptide that is cleaved to generate a 69 aa residue mature protein which lacks potential glycosylation sites. In vitro, CCL18 mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10 and IL-13, and inhibited by IFN-γ. CCL18 mRNA is also expressed by GM-CSF/IL-4-induced monocyte-derived dendritic cells. In vivo, CCL18 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells. Recombinant CCL18 has been shown to chemoattract naive T cells, but not monocytes or neutrophils., UnitProt ID: P55774
UPC:
12350000
Condition:
New
Availability:
3 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
RC315-29.SIZE.10ug


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