Human TIGIT Antibody (20A9), mAb, Mouse,40ug

Catalog No.: C08-0412-558
Manufacturer No.: A01981-40
Manufacturer Name: GenScript USA Inc
Quantity: 1
Unit of Measure: EA

Price: $242.14

List Price: $269.05

T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VS&trade3, is a type I transmembrane protein, which belongs to the PVR family of immunoglobulin-like domain containing proteins. It is composed of an immunoglobulin variable

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Description
Specifications

T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VS™3, is a type I transmembrane protein, which belongs to the PVR family of immunoglobulin-like domain containing proteins. It is composed of an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on activated T cells, follicular T helper, memory T cells, and regulatory T cells and NK cells. TIGIT binds to CD155 (PVR) with high affinity and it regulates T-cell mediated immunity via the CD226/TIGIT-PVR pathway. TIGIT also serves as a negative regulator of NK and T cell activation. Human TIGIT Antibody (20A9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with TIGIT.

UPC:: 41122409
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: A01981-40

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