Animal-free Recombinant Human IL-17F is a homodimeric glycoprotein with an apparent molecular mass of 38 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, which contributes to stability in cell growth media and other applications. IL-17 is commonly associated with allergic responses. IL-17 induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1beta, TGF beta, and TNF alpha), chemokines (including IL-8, GRO alpha, and MCP-1), and prostaglandins (e.g., PGE2) from many cell types (fibroblasts, endothelial cell, epithelial cells, keratinocytes, and macrophages). The release of cytokines causes many functions, such as airway remodeling, a characteristic of IL-17 responses.
- UPC:
- 12350000
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- HZ-1116-100
