General description
May contain or form low levels of calcium fluoride during storage. Presence of this does not impact the specification values.
Application
Convenient form of anhydrous HF, stable up to 50°C. Has been used for the preparation of β-fluoroamines from amino alcohols and for the fluorination of acetylenes.
Used together with hypervalent iodine(III) reagents for ipso-fluorination of para-substituted phenols providing cyclohexadienones. Employed with Selectfluor™ (Catalog No. 439479) for geminal fluorination of 2,2-diaryl-1,3-dithiolanes.
Reactant for preparation of:
- Epimers of shikimic acid with the features of fucosylated glycans via zinc-mediated reductive ring opening followed by a Barbier reaction
- Vaccinia H1-related (VHR) phosphatase inhibitor with a nonacidic phosphate-mimicking core structure
- Candidates for nucleic acid drugs
- ω-substituted gem-difluoroalkanes by oxidative desulfurization-difluorination
Reagent for:
- Halofluorination reactions
Legal Information
Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
- UPC:
- 51294700
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 184225-25G