Biochem/physiol Actions HZ-166 is a potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α:2- and α:3-GABAARs. HZ-166 exhibits antihyperalgesic properties in mice models of
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HZ-166 is a potent, non-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs. HZ-166 exhibits antihyperalgesic properties in mice models of neuropathic and inflammatory pain, without sedation and motor impairment.
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