nterleukin-11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 has multiple effects on both hematopoietic and non-hematopoietic cells. Many of the biological effects described for IL-11 overlap with those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell-dependent development of specific immunoglobulin-secreting B cells. Recombinant Human IL-11 Fc Chimera produced in CHO cells is a polypeptide chain with the C-terminal human IgG1 Fc fragment. A fully biologically active molecule, rhIL-11 a molecular mass of 51.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript. For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51382902
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Z03405-1
- Model Number:
- CHM01R619
- Temperature Control Device:
- Yes
