General description
A non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC50 = 3 µM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inhibitor of the IL-2/IL-2Rα interaction
Product does not compete with ATP.
Reversible: no
Target IC50: 3 µM against IL-2/IL-2Rα interaction
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Emerson, S.D., et al. 2003. Protein Science12, 811.
Tilley, J.W., et al. 1997. J. Am. Chem. Soc.119, 7589.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51173102
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 407621-5MG
- CAS:
- 1217448-66-2