General description
Imidazole is an aromatic heterocyclic compound with a five-membered planar ring. It is an amphoteric compound because of the presence of both an acidic NH and a basic nitrogen atom. Imidazole is an essential component of many important molecules including natural products, bioactive molecules, ionic liquids, and imidazolium. It serves as a building block for the synthesis of various drug molecules.
Application
Imidazole can be used as a catalyst:
- For the silylation of alcohols, carboxylic acids, and amines in the presence of silyl chloride in DMF.
- In the peptide coupling using the triphenyl phosphite.
- To prepare acid chlorides from the corresponding carboxylic acids and phosgene.
It can also be used in the following reactions:
- Imidazole-PPh3/I2 catalytic system used in the conversion of alcohols into iodides
- Imidazole-PPh3/I2 is used in the diol deoxygenation reaction.
Excellent for buffers in the range of pH 6.2-7.8
Other Notes
For titration of aspartic acid and glutamic acid
- UPC:
- 51282800
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 56750-100G