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ims2186

IMS2186

Sigma Aldrich

Catalog No.
C15-1200-678
Manufacturer No.
I7160-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG
Price: $280.71
List Price: $311.90

Biochem/physiol Actions IMS2186 is an anti-proliferative and anti-angiogenic agent. Apparently IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α.

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Biochem/physiol Actions

IMS2186 is an anti-proliferative and anti-angiogenic agent. Apparently IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss.

UPC:
41115812
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
I7160-5MG

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