Indole-5-carboxaldehyde

Application

Indole-5-carboxaldehyde can be used as a reactant in the:

• Preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents
• Preparation of analogs of botulinum neurotoxin serotype A protease inhibitors
• Stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes
• Synthesis of para-para stilbenophanes by McMurry coupling
• Stereoselective synthesis of heteroaromatic (E)-α,β-unsaturated ketones from aldehydes
• Structure-based drug design of aurora kinase A inhibitors
• Preparation of 5-indolyl linked 15- and 18-membered azacrown ethers to study their cation-π interactions.
• Preparation of bibenzimidazole derivatives substituted 5-indolyl moiety in the study of inhibition of topoisomerase I activity.
• Synthesis of (5-(4-(3,4,5-trimethoxybenzoyl)-1H-imidazol-2-yl)-1H-indol-2-yl)(3,4,5-trimethoxyphenyl)methanone and radioiodinated indolochalcone.