inhibitor of pkc and na+/k+ atpase found in chelidonium and (c08-0489-323)

Inhibitor of PKC and Na+/K+ ATPase found in Chelidonium and Zanthoxylum. It decreases LPS-stimulated pro-inflammatory cytokine expression and induces apoptosis in hepatoma cells. (C08-0489-323)

Thomas Scientific

Catalog No.: C08-0489-323
Manufacturer No.: C2818-5 mg
Manufacturer Name: LKT Laboratories, Inc
Quantity: 1
Unit of Measure: EA

Price: $497.31

List Price: $552.57

Chelerythrine is a benzophenanthridine alkaloid found in Chelidonium and Zanthoxylum that exhibits anti-inflammatory and anticancer activities. Chelerythrine inhibits PKC and Na+/K+ ATPases.

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Description
Specifications

Chelerythrine is a benzophenanthridine alkaloid found in Chelidonium and Zanthoxylum that exhibits anti-inflammatory and anticancer activities. Chelerythrine inhibits PKC and Na+/K+ ATPases. In LPS-stimulated animal models, chelerythrine decreases levels of TNF-a, IL-6, and myeloperoxidase. In hepatoma cells, this compound decreases the mitochondrial membrane potential, increases release of cytochrome C, stimulates cleavage of PARP, alters the Bax/Bcl-xl ratio, and induces apoptosis.

UPC:: 41122409
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: C2818-5 mg
CAS:: 3895-92-9

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