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insl5/insl7 hybrid human

INSL5/INSL7 HYBRID HUMAN

Sigma Aldrich

Catalog No.
C15-1717-785
Manufacturer No.
SRP3304-25UG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA
Price: $618.86
List Price: $687.62

Biochem/physiol Actions The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide

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Biochem/physiol Actions

The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.7 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain.

Physical form

Lyophilized with no additives.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

UPC:
42211711
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
SRP3304-25UG
Product Size:
25/µG

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