INSOLUTION SRT1720 HCL (C15-1305-029)

General description

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

An enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
SIRT3

Reversible: yes

Secondary Target
p300 HAT

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Physical form

A 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Other Notes

Baur, J.A., et al. 2012. Nat. Rev. Drug Discov.11, 443.
Minor, R.K., et al. 2011. Sci. Rep.1, 70.

Huber, J.L., et al. 2010. Future Med. Chem.2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem.285, 8340.
Jin, L., et al. 2009. Protein Sci.18, 514.
Feige, J.N., et al. 2008. Cell Metab.8, 347.
Milne, J.C., et al. 2007. Nature450, 712.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Empirical Formula: C₂₅H₂₃N₇OS · xHCl. Quality Level: 100. Assay: ≥. 98% (HPLC). form: liquid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light. storage temp.: −. 70°C. InChI: 1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31. /h1-8,13,15-16,26H,9-12,14H2,(H,29,33). 1H. InChI key: DTGRRMPPXCRRIM-UHFFFAOYSA-N. Storage Class Code: 10 - Combustible liquids. WGK: WGK 3. Flash Point(F): 188.6 °F. Flash Point(C): 87 °C.