Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC 50 of 9.8 nM for RGD-binding α4β1 . Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC 50 of 12.9 nMIn VitroIntegrin modulator 1 (2-10 μg/mL; 30 min) significantly increases Jurkat E6.1 cell adhesion. Integrin modulator 1 (1-100 nM; 1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6.1 cells. Integrin modulator 1 (1 nM-10 μM; 30 min) significantly increases the binding of HUTS-21 antibody to Jurkat E6.1 cells in a concentration-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:α4β1 9.8 nM (IC 50 ). Specification: 0.99 Molecular Formula: C13H14N2O4 Molecular Weight: 262.26 PubChem CID: 154734317 Isomeric SMILES: CC1=CC=CC=C1NC(=O)N2C(CC2=O)CC(=O)O
- UPC:
- 51473404
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- I646298-100mg
- CAS:
- 2023788-32-9
- Product Size:
- 100mg
