Potent, cell permeable inhibitor of PHD2 (IC50 = 21 nM) with over 100-fold selectivity compared to inhibition of JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH (IC50s > 100 &muM) inhibits HIF-1&alpha hydroxylation in RCC4 cells at 50
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