IRBP (1-20), human (C09-1140-109)

IRBP (1-20), human contains a major epitope for the H-2 b haplotype. IRBP (1-20), human induces experimental autoimmune uveoretinitis (EAU) in H-2 b mice.In VivoIRBP (1-20), human TFA induces EAU. For determination of proliferative and cytokine responses, lymph node and spleen cells are collected 21 days after immunization and are stimulated in culture with the appropriate antigen. Cells of C57BL/6 mice and 129/J mice immunized with IRBP (1-20), human TFA proliferated in response to the peptide. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: C57BL/6 (H-2 bbDosage: 200, 300 μg Administration: I.h.; After 21 days Result: C57BL/6 (H-2 bb ) also developed disease, albeit with a lower average score than C57BL/6.Form:Solid. Specification: 0.99 Molecular Formula: C101H164N24O28S Molecular Weight: 2194.59