Isocitric Dehydrogenase (NADP) from porcine heart (C15-1291-469)

Catalog No.: C15-1291-469
Manufacturer No.: I2002-250MG
Manufacturer Name: Sigma-Aldrich
Quantity: 250
Unit of Measure: MG

Price: $1,361.14

List Price: $1,512.38

Application Isocitric dehydrogenase (IDH) has been used: for in vitro activity assay to study the effects of thorium on citric acid cycle enzymes in the mitochondrial respiration pathway as a standard to measure the impact of temperature on

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Description
Specifications

Application

Isocitric dehydrogenase (IDH) has been used:

for in vitro activity assay to study the effects of thorium on citric acid cycle enzymes in the mitochondrial respiration pathway
as a standard to measure the impact of temperature on nicotinamide diphosphate (NADP)-IDH activity
in isocitrate assay

Biochem/physiol Actions

Isocitrate dehydrogenase (IDH) is a homodimeric enzyme and participates in several processes such as adapting to hypoxia, histone demethylation, and DNA modification. This enzyme has three isoforms like IDH₁, IDH₂, and IDH₃.

Unit Definition

One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37 Â°C.

Physical form

Solution in 50% glycerol in EDTA buffer salts, pH 6.0

UPC:: 41142052
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: I2002-250MG

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