A competitive inhibitor of human lysosomal β-glucosidase (Ki = 0.016-0.025 µM; IC50 = 0.06 µM) that interacts with the catalytic pocket of β-glucosidase, acting as a chemical chaperone that stabilizes and/or promotes the folding of the enzyme; increases lysosomal β-glucosidase activity by 2- to 3-fold in mutant N370S Gaucher fibroblasts.
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- UPC:
- 12352200
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 16137-10
- Model Number:
- C817H83
- Temperature Control Device:
- Yes