Isofagomine D-Tartrate is an inhibitor of human acid β-glucosidase. Isofagomine D-Tartrate is used in the treatment of Gaucher disease. Isofagomine D-Tartrate has been shown to increase lysosomal β-glucosidase activity by 2- to 3-fold in mutant N370S Gaucher fibroblasts. By interacting with the catalytic pocket of β-glucosidase, Isofagomine D-Tartrate acts as a chemical chaperone that increases the amount of β-glucosidase by stabilizing and/or promoting the folding of the enzyme. Isofagomine D-Tartrate is also known as Afegostat tartrate, (3R,4R,5R)-5-(Hydroxymethyl)-3,4-piperidinediol (2S,3S)-2,3-Dihydroxybutanedioate, and 5R-(hydroxymethyl)-3R,4R-piperidinediol, mono 2S,3S-dihydroxybutanedioate. Molecular Formula: C10H19NO9 Molecular Weight: 297.26 PubChem CID: 56841032 Isomeric SMILES: C1[C@@H]([C@H]([C@@H](CN1)O)O)CO.[C@H]([C@@H](C(=O)O)O)(C(=O)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/I343323-SCI_f26d52339853d311fe50dfff5fbcbd3b.pdf
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- I343323-10mg
- CAS:
- 957230-65-8
- Product Size:
- 10mg
- Precautionary Statement Codes:
- P264
