ISOLIENSININE (C005B-309693)

Catalog No.: C005B-309693
Mfr. No.: SML3024-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $214.73

List Price: $238.59

Biochem/physiol Actions Isoliensinine is a major bisbenzylisoquinoline alkaloid found in the seed-embryos of Nelumbo nucifera that exhibits potent anticancer, anti-diabetic and anti-pulmonary fibrosis effects. It induces apoptosis in triple

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Biochem/physiol Actions

Isoliensinine is a major bisbenzylisoquinoline alkaloid found in the seed-embryos of Nelumbo nucifera that exhibits potent anticancer, anti-diabetic and anti-pulmonary fibrosis effects. It induces apoptosis in triple negative breast cancer cells through induction of ROS and p38 MAPK/JNK activation, while showing only mild effects on normal MCF-10A cells. Isoliensinine shows chemosensitizing properties in several cancer cells. It appears that if augments cisplatin uptake int cancer cells.

UPC:: 51111862
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3024-5MG
CAS:: 6817-41-0

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