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Isoxazole 9 (ISX-9) (C007B-196329)

Catalog No.
C007B-196329
Mfr. No.
I408314-1ml
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $338.49
List Price: $376.10

InformationIsoxazole 9 (ISX-9) Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs). Isoxazole 9 (Isx-9) activates multiple pathways including TGF-β

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InformationIsoxazole 9 (ISX-9) Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs). Isoxazole 9 (Isx-9) activates multiple pathways including TGF-β induced epithelialIn vitroIn NSPCs, isoxazole 9 increases cell number, and promotes cell differentiation. In OPCs, isoxazole 9 induces cell damage. In outgrowth EPCs, isoxazole 9 decreases tube formation without effect on early EPCs.In vivoIn mice, isoxazole 9 (20 mg/kg, i.p.) crosses the BBB and increases proliferation of neuroblasts and neurogenesis via Mef2-specific mechanisms in the hippocampal SGZ. Isoxazole 9 (20 mg/kg, i.p.) also increases differentiation and dendritic complexity of immature neurons and improves memory. In MWM, isoxazole 9 improves spatial memory.Cell Datacell lines:MKN45, EBC-1, Hs746T, SNU-5, A549, SNU-1 and MKN74Concentrations:~50 μMIncubation Time:48 hPowder Purity:≥98%. Specification: 10mM in DMSO Molecular Formula: C11H10N2O2S Molecular Weight: 234.27
UPC:
51111726
Condition:
New
Availability:
8-12 weeks
Weight:
0.85 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
I408314-1ml
CAS:
832115-62-5
Product Size:
1ml

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