The main component (>80%) of the anthelmintic, ivermectin binds to glutamate-gated chloride channels, inducing irreversible channel opening (EC50 = 104 nM).
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The main component (>80%) of the anthelmintic, ivermectin; binds to glutamate-gated chloride channels, inducing irreversible channel opening (EC50 = 104 nM).
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