General description
- Jones reagent is a solution of chromium trioxide in aqueous sulfuric acid.
- Using acetone as a reaction solvent, the reagent is usually used for the oxidation of primary and secondary alcohols to carboxylic acids and ketones, respectively.
- The oxidation is very rapid and exothermic.
- The reagent tolerates a variety of functionalities, such as, for example, unsaturated bonds, which are rarely oxidized.
For a comprehensive review of chromium-based reagents, see "Oxidation of Alcohols to Aldehydes and Ketones" by Tojo and Fernández, Springer Berlin, 2006, 1-97.
Application
Jones reagent can be used:
- In the oxidative cleavage of various alkenes into carboxylic acids and ketones using a catalytic amount of osmium tetroxide.
- To prepare symmetrical binaphthols by oxidative dehydrodimerization of substituted naphthols.
- To synthesize acyl-naphthols and substituted isocoumarins from 2-(4-hydroxy-but-1-ynyl)benzaldehydes.
- UPC:
- 12352100
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 758035-25ML