Application
K-252a has been used:
- as a tropomyosin receptor kinase (Trk) inhibitor to study the role of TrkA signaling in rats
- as a Trk inhibitor for inducing in vitro injury in retinal Müller glial cells to study the effects of cord blood serum (CBS)
- as a general protein kinase inhibitor to study its effect on in vitro human somatic testicular cell reassembly
Biochem/physiol Actions
K-252a is a selective inhibitor of tyrosine protein kinase. It targets a wide range of protein kinases with IC50 values between 3 and 25nM and the neurotrophin receptor-tropomyosin receptor kinase.
- UPC:
- 51172827
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- K1639-100UG