General description
A potent alkaloid inhibitor of mannosidase I. An ineffective inhibitor of mannosidase II and the endoplasmic reticulum α-mannosidase.
A potent alkaloid inhibitor of mannosidase I. Does not affect mannosidase II and the endoplasmic reticulum α-mannosidase.
Biochem/physiol Actions
Cell permeable: no
Primary Target
mannosidase-1
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Weng, S., and Spiro, R.G. 1996. Arch. Biochem. Biophys.325, 113.
Kayakiri, H., et al. 1991. Chem. Pharm. Bull. 39, 1378.
Elbein, A.D., et al. 1990. J. Biol. Chem. 265, 15599.
Iwami, M., et al. 1987. J. Antibiotic. 40, 612.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51301904
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 422500-1MG