General description
The KitAlysis™ High Throughput Buchwald–Hartwig Amination Reaction Screening Kit enables chemists to quickly and efficiently screen Buchwald–Hartwig C–N cross-coupling reaction conditions. Quick identification of optimal conditions allows faster scale-up of the synthetic reaction. All required chemicals come pre-weighed for ease of use. A step-by-step user guide and experimental excel sheets are available for download to facilitate the process.
Application
There are four possible screens that can be run based upon the user’s substrates. Step-by-step user guides and a downloadable experimental excel sheets for each screen is provided in the below hyperlinks.
Two Solvents, Weak Base (Cs2CO3)
Download the experimental excel file here
Two Solvents, Strong Base (NaOt-Bu)
Download the experimental excel file here
One Solvent (Dioxane), Two Bases
Download the experimental excel file here
One Solvent (DMAc), Two Bases
Download the experimental excel file here
Each kit contains 4 screening sets that contain the following:
Each customizable screening kit contains
- 12 X 2 pre-weighed catalysts (1 μmol) in individual microvials with magnetic stir bars
- 2 bases (NaOt-Bu and Cs2CO3)
- 2 degassed anhydrous solvents (dioxane and DMAc) in ampules
- 2 substrate reaction vials with stir bars
- 1 internal standard
- 4 reaction block replacement films
Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).
Features and Benefits
- Designed and tested by synthetic chemists
- Easily run 24-microscale reaction in parallel
- 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration
- Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks
Legal Information
KitAlysis is a trademark of Sigma-Aldrich Co. LLC
- UPC:
- 60104007
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- KITALYSIS-CN-1KT
