L-368,899 hydrochloride (C09-0934-400)

L-368,899 hydrochloride is a potent, non-peptide oxytocin receptor antagonist. L-368,899 hydrochloride has shown a 40-fold selectivity over Vasotocin V1a and V2 receptors. L-368,899 hydrochloride has been shown to antagonize oxytocin-induced uterine contractions in vitro. L-368,899 hydrochloride is a useful tool for investigating the role of oxytocin, and studies in primates have shown L-368,899 hydrochloride to reduce a number of behaviours such as food sharing, sexual activity and caring for infants. L-368,899 hydrochloride is also known as L-368899 free base, (S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tolylpiperazin-1-ylsulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide, and 1-(((7,7-dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo[2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperazine. Specification: >97% Molecular Formula: C26H42N4O5S2•HCl Molecular Weight: 591.22 PubChem CID: 9872389 Isomeric SMILES: CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)C[C@@]34CC[C@@H](C3(C)C)C[C@@H]4NC(=O)[C@H](CCS(=O)(=O)C)N Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/L332119-SCI_bd9a2210f869ac844cfd569c53e50580.pdf