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L-alpha-Lysophosphatidylcholine from Glycine max (soybean) (C15-1290-987)

Catalog No.
C15-1290-987
Manufacturer No.
L0906-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG
Price: $184.93
List Price: $205.48

Biochem/physiol Actions Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the

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Biochem/physiol Actions

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

Packaging

Packaged under Argon.

Preparation Note

Prepared by the action of phospholipase A on soybean L-α-phosphatidylcholine (P 6263).

UPC:
51183108
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
L0906-25MG


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