L-Buthionine-sulfoximine (C15-1284-335)

Catalog No.: C15-1284-335
Manufacturer No.: B2515-1G
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: GR

Price: $761.14

List Price: $845.71

Application L -Buthionine-sulfoximine has been used: as a selective activator for the induction of ferroptosis in rat apoptotic cells as an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of

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Description
Specifications

Application

L-Buthionine-sulfoximine has been used:

as a selective activator for the induction of ferroptosis in rat apoptotic cells
as an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barley
as a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1β expression in murine alveolar macrophages

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

UPC:: 51412002
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: B2515-1G

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