L-(+)-Ergothioneine (C09-0932-719)

Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. Ergothioneine can scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone. The compound could be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105).An antioxidant and free radical scavengerApplication：L - (+) - ergot sulfur is suitable for studying its reactivity with 2,2 '- and 4,4' - bipyridine disulfides (2-Py-S-S-2-Py and 4-Py-S-S-4-Py). It can also be used for the incubation of experimental cells and for in vitro kinase activity measurement of ATM (Ataxia telangiectasia mutation) or ATR (ATM - and RAD3- related).L - (+) - ergot has been used to: 1. As a component of the cumulus oocyte complex (COC) maturation medium, its protective effect on lipid peroxidation formation was tested; 2. As an antioxidant compound, it is used to detect type 2 diabetes patients; 3. As a positive control for soluble carrier protein 22A4 (SLC22A4) transport detection. Specifications and Purity: ≥98%. MDL Number: MFCD00167474. Molecular Formula: C9H15N3O2S. Molecular Weight: 229.3. EC Number: 207-843-5. PubChem CID: 5351619. Isomeric SMILES: C[N+](C)(C)[C@@H](CC1=CNC(=S)N1)C(=O)[O-]. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/L134175-SCI_57767a1baf9472bba996c1147d9f793e.pdf.