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L-LEUCINE NON-ANIMAL SOURCE CELL CULTURE TESTED MEETS EP JP & USP TESTING SPECIFICATIONS (C005B-455828)

Catalog No.
C005B-455828
Mfr. No.
L8912-10MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
10
UOM
MG
Price: $61.94
List Price: $68.82

General description Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.

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General description

Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.

Application

L-Leucine has been used:

  • as a hypertrophic agent to monitor its effects on myotubes.
  • as a component of PMG media for culturing yeast.
  • in myotube protein synthesis analysis in skeletal muscle cells.
  • to study its effects on hepatic lipid metabolism.

Biochem/physiol Actions

Leucine plays a role in intracellular signaling, gene transcription, and translation. It promotes the synthesis of protein by activating the mammalian target of the rapamycin (mTOR) signaling pathway in placental cells, skeletal muscles, and adipose tissue. Leucine inhibits protein degradation and promotes mitochondrial biogenesis, glucose metabolism, and fatty acid oxidation to provide energy for protein synthesis.

Other Notes

The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

UPC:
51180000
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
L8912-10MG
CAS:
61-90-5

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