Cell Biology Reagents

Fluorogenic CPP32/Apopain substrate. Cleavage of this substrate by CPP32/Apopain shows Michaelis-Menten kinetics (K m = 9.

A reversible caspase-4 (ICH-2) inhibitor. A reversible caspase-4 inhibitor.

Immunogen 16 amino acids near the amino terminus of human Caspase-5. Application Used as a blocking peptide in immunoblotting applications.

Immunogen 16 amino acids near the carboxy terminus of human caspase-7. Application Used as a blocking peptide in immunoblotting applications.

Antigen: mixture of synthetic peptides corresponding to rat caspase-9 amino acids 345-359 and 366-383 Host: rabbit Cross Reactivity: (+) human, mouse, and rat caspase-9 Application(s): WB CTD is a novel isoform of rat caspase-9 in which the

Antigen: human caspase-9 amino acids 299-318 Host: rabbit Application(s): WB Caspase-9 is activated by granzyme B, CPP32, or by binding Apaf-1. Activated caspase-9 cleaves and activates caspase-3, playing a central role in cell death induced by a

Biochem/physiol Actions Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer′s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane

Biochem/physiol Actions Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer′s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane

Biochem/physiol Actions Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer′s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane

An intermediate used in the synthesis of potent DP2 receptor antagonists.

An intermediate used in the synthesis of potent DP2 receptor antagonists.

Cell Line Origin Human Caucasian lung Cell Line Description Established from normal lung tissue of a 35 year old Caucasian male who died of a class 1-2 astrocytoma. The donor who was maintained for organ transplantation prior to removal of the lung.