Apoptosis Inhibitors

Application 6-bromoindirubin-3&#8242-oxime (BIO) has been used: in MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) cell proliferation assay as a medium supplement in embryonic stem cells (ESCs) for the inhibition of glycogen

BOLD-100 (NKP-1339: IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the

BOLD-100 (NKP-1339: IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the

BOLD-100 (NKP-1339: IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the

BOLD-100 (NKP-1339: IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the

BOLD-100 (NKP-1339: IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis , and induction of apoptosis via the

A cell-permeable dipeptidylboronate compound that selectively inhibits 20S proteasome &#9465 ChTL/chymotrypsin- over &#9461 CL/caspase- and &#9462 TL/trypsin-like activity ( k inact / K i = 38,000, 5,700, and &lt100 M -1 s -1 , respectively, in

InformationBV-6 is a SMAC mimetic, dualcIAPandXIAPinhibitor.In vitroBV6 inhibits the cell viability of HCC193 NSCLC cells with IC50 of 7.2 μM, induces apoptosis in both HCC193 and H460 cell lines, and also significantly enhances the radiosensitivity

InformationBV-6 is a SMAC mimetic, dualcIAPandXIAPinhibitor.TargetscIAP : XIAPIn vitroBV6 inhibits the cell viability of HCC193 NSCLC cells with IC50 of 7.2 μM, induces apoptosis in both HCC193 and H460 cell lines, and also significantly enhances

InformationBV-6 is a SMAC mimetic, dualcIAPandXIAPinhibitor.TargetscIAP : XIAPIn vitroBV6 inhibits the cell viability of HCC193 NSCLC cells with IC50 of 7.2 μM, induces apoptosis in both HCC193 and H460 cell lines, and also significantly enhances

InformationBV-6 is a SMAC mimetic, dualcIAPandXIAPinhibitor.TargetscIAP : XIAPIn vitroBV6 inhibits the cell viability of HCC193 NSCLC cells with IC50 of 7.2 μM, induces apoptosis in both HCC193 and H460 cell lines, and also significantly enhances

InformationBV-6 is a SMAC mimetic, dualcIAPandXIAPinhibitor.TargetscIAP : XIAPIn vitroBV6 inhibits the cell viability of HCC193 NSCLC cells with IC50 of 7.2 μM, induces apoptosis in both HCC193 and H460 cell lines, and also significantly enhances