Apoptosis-related Peptides

General description PRKD1 gene encodes PKD1 (protein kinase D1), that belongs to the protein kinase D family. It is a serine/threonine kinase, which is expressed in cells of the normal mammary gland.

Immunogen Synthetic peptide directed towards the N terminal region of human PTDSS1 Biochem/physiol Actions PTDSS1 is a multi-pass membrane protein. It belongs to the phosphatidyl serine synthase family.

General description PTP-U, a member of the receptor class 2B subfamily of protein-tyrosine phosophatases, is involved in regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. It forms

General description The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation

RAB11B is a GTP-binding protein that regulates diverse cellular functions.It is expressed in vesicular compartments in parietal and epithelial cells.

General description The previously assigned protein identifier A8K2G5 has been merged into O95398. Full details can be found on the UniProt database.

General description Members of the RAS (see HRAS: MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors

Immunogen Synthetic peptide directed towards the C terminal region of human RBM42 Biochem/physiol Actions RBM42 belongs to the RRM RBM42 family and it contains 1 RRM (RNA recognition motif) domain. The functions of RBM42 remain unknown.

General description The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is

Receptor-interacting protein kinase 1 (RIPK1) is known to activate NF-&#954B signaling and is also known to modulate apoptosis and caspase-8 stimulation. Rabbit Anti-RIPK1 antibody associates with human, and bovine RIPK1.

Immunogen Synthetic peptide directed towards the middle region of human RNF43 Biochem/physiol Actions RNF43 is a HAP95 (AKAP8L) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer. Sequence Synthetic peptide

General description Ribosomal protein L35 (RPL35) gene codes for a ribosomal protein, a constituent of the 60S subunit. It is located on human chromosome 9q33.