Apoptosis-related Peptides

A cell-permeable peptide that prevents apoptotic cell death by directly binding to the voltage-dependent anion channel (VDAC) and blocking its activity. Leads to the inhibition of cytochrome c release and loss of mitochondrial membrane potential

Antigen: internal central human Bim amino acids Host: rabbit Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) Applications: IHC and WB Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w

Antigen: internal central human Bim amino acids Host: rabbit Cross Reactivity: (+) human, mouse, and rat Bim/BOD (IN) Applications: IHC and WB Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, -xL, and -w

The Caspase 2/p18 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Caspase 2/p18. This antibody recognizes human, mouse antigen.

Amino Acid Sequence Ac-Asp-Glu-Val-Asp-7-AFC Application Ac-DEVD-7-AFC (N-acetyl-asp-glu-val-asp-7-amino-4-trifluoromethyl coumarin) is used as a cell penetrating fluorogenic CED-related caspase substrate.

The Caspase 3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Caspase 3. This antibody recognizes human,mouse,rat antigen.

Amino Acid Sequence Ac-Val-Glu-Thr-Asp-AMC Application Fluorogenic caspase 8 substrate has been used to measure caspase 8 activity in Jurkat cell lysates. Biochem/physiol Actions The peptide Ac-Val-Glu-Thr-Asp-AMC, or Ac-VETD-AMC, is a

Amino Acid Sequence Ac-Leu-Glu-His-Asp-pNA Application Caspase 9 is an initiator caspase that cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic

Amino Acid Sequence Z-Tyr-Val-Ala-Asp-AFC Biochem/physiol Actions Z-Tyr-Val-Ala-Asp-AFC, or Z-YVAD-AFC, is a fluorogenic substrate for caspase-1. The parent tetrapeptide is derived from the cleavage site for pro-interleukin b1, as the minimal

Caspase Substrate

Immunogen 16 amino acids near the carboxy terminus of human Caspase-1. Application Used as a blocking peptide in immunoblotting applications.

Immunogen 15 amino acids near the center of human Caspase-1. Application Used as a blocking peptide in immunoblotting applications.