Apoptosis-related Peptides

Specificity Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.

General description This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

General description Caspase-1 is also known as interleukin-1&#946: converting enzyme (ICE). It is located on chromosome 11q22.

General description Caspase-4 (CASP-4), also known as Caspase-11 (CASP-11), or Protease ICH-3, and encoded by the gene names Casp4, Casp11, Caspl, and Ich3, is a member of the peptidase C14A family and might be involved in ER-stress induced

Immunogen Synthetic peptide directed towards the N terminal region of human CCNL2 Biochem/physiol Actions CCNL2 belongs to the cyclin family, Cyclin L subfamily. CCNL2 is a transcriptional regulator which participates in regulating the pre-mRNA

General description This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype,

General description Antigen-presenting glycoprotein CD1d (UniProt Q63493: also known as CD1D antigen, CD1d1 antigen, T-cell surface glycoprotein CD1d) is encoded by the Cd1d (also known as Cd1d1) gene (Gene ID 25109) in rat species. CD1d is a

General description The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional

General description CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells: its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by

General description Anti-CD45 antibody detects endogenous levels of total CD45 protein. The CD45 (cluster of differentiation 45) gene is mapped to human chromosome 1q31.

Immunogen Synthetic peptide directed towards the N terminal region of human CDC25B Application Anti- CDC25B (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1 &#956g/ml. For immunohistochemistry of

General description CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization