Neurotropic Receptor Modulators

S100B, monkey: S100B belongs to the S100 family, which containing 2 EF-hand calcium-binding motifs. In humans, S100B protein is encoded by the S100P gene located at 4q16, but genes that encode other numbers of s100 family proteins are almost located

Application SB265610 has been used: as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR) as a CX-chemokine receptor type 1

Application SB265610 has been used: as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR) as a CX-chemokine receptor type 1

Cell Line Origin Human neuroblastoma Cell Line Description SH-SY5Y is a thrice-cloned sub-line of bone marrow biopsy-derived line SK-N-SH (Sigma catalogue no. 86012802).

Application SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies. Biochem/physiol Actions SIB 1893 non-competitively inhibits glutamate-induced increase in Ca 2+ at human metabotropic glutamate receptor

A peptidyl toxin present in the venom of African tarantula, Hysterocrates gigas that acts as a high affinity, reversible blocker of Ca v 2.3 (&#9451E, R-type) channels (IC 50 = 15-30 nM).

General description Spermine&nbsp:is a polyamine, which functions as a free radical scavenger. It modulates gene expression, chromatin stabilization and prevents DNA damage.

General description Spermine&nbsp:is a polyamine, which functions as a free radical scavenger. It modulates gene expression, chromatin stabilization and prevents DNA damage.

General description Spermine&nbsp:is a polyamine, which functions as a free radical scavenger. It modulates gene expression, chromatin stabilization and prevents DNA damage.

Amino Acid Sequence Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 General description Research area: Cell Signaling Substance P is a member of the tachykinin family of peptides. It is encoded by the tachykinin precursor 1 (TAC1) gene

Amino Acid Sequence Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 General description Research area: Cell Signaling Substance P is a member of the tachykinin family of peptides. It is encoded by the tachykinin precursor 1 (TAC1) gene

Amino Acid Sequence Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 General description Research area: Cell Signaling Substance P is a member of the tachykinin family of peptides. It is encoded by the tachykinin precursor 1 (TAC1) gene