Other Receptor Modulators

C2BBE1 CONTROL CELLS WITH MDR1/BCRP EVALUATION KIT

C2BBE1 CONTROL CELLS WITH MDR1/BCRP KO CELLS

Bradykinins bind and activate two GPCRs, termed B1 and B2 (gene names BDKRB1 and BDKRB2, respectively), which signal through Gq and Gi. B2 is widely expressed in a constitutive fashion, whereas B1 expression is induced during inflammation.

CD16 is a cluster of differentiation molecule found on the surface of natural killer (NK) cells, monocytes and macrophages. It can be used to isolate populations of NK cells by antibodies directed towards CD16, using fluorescent-activated cell

CD16 is a cluster of differentiation molecule found on the surface of natural killer cells, monocytes and macrophages. It can be used to isolate populations of these cells by antibodies directed towards CD16, using fluorescent-activated cell sorting

CXCR4 is a receptor for the C-X-C chemokine SDF-1 (Stromal Cell-Derived Factor 1). It is involved in haematopoiesis and cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, cerebellar

FFA2 (GPR43) is a 330-amino acid G-protein coupled receptor that binds to fatty acid. FFA2 is highly selective expressed in leukocytes, which suggests a role in the recrui&tradeent of these cell populations toward sites of bacterial infection.

OX40 (CD134) is a member of the TNFR/TNF superfamily. Costimulatory signals from OX40 to a conventional T cell promotes division and survival, augmenting the clonal expansion of effector and memory populations as they are being generated to antigens.

General description CL264 is a hydrophilic molecule. CL264,an adenine analog, is a potent and selective toll-like receptor 7 (TLR7) agonist with no TLR8-stimulating potency.

General description CL264 is a hydrophilic molecule. CL264,an adenine analog, is a potent and selective toll-like receptor 7 (TLR7) agonist with no TLR8-stimulating potency.

General description Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin.

Cytotoxic T lymphocyte-associated molecule-4 (CTLA-4) is a cell surface molecule that is closely related to CD28, and a powerful negative regulator of T cell activation. Structurally, CTLA-4 is a member of the Ig superfamily, having a single