Laboratory

The dominant alkaloid found in tobacco plants that acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs Kis = 481 and 11.1 nM for &alpha3&beta4 and &alpha4&beta2 subtypes, respectively).

The dominant alkaloid found in tobacco plants that acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs Kis = 481 and 11.1 nM for &alpha3&beta4 and &alpha4&beta2 subtypes, respectively).

An internal standard for the quantification of (&plusmn)-nicotine by GC- or LC-MS.

An internal standard for the quantification of (&plusmn)-nicotine by GC- or LC-MS.

An internal standard for the quantification of (&plusmn)-nicotine by GC- or LC-MS.

An internal standard for the quantification of (&plusmn)-nicotine by GC- or LC-MS.

An inhibitor of p53-Mdm2 interaction (IC50 = 0.09 &microM) induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53.

An inhibitor of p53-Mdm2 interaction (IC50 = 0.09 &microM) induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53.

An inhibitor of p53-Mdm2 interaction (IC50 = 0.09 &microM) induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53.

An inhibitor of p53-Mdm2 interaction (IC50 = 0.09 &microM) induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53.

A carnitine ester that inhibits carnitine-acylcarnitine translocase (IC₅₀ = 33 &muM).

A carnitine ester that inhibits carnitine-acylcarnitine translocase (IC₅₀ = 33 &muM).