Life Science

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

12(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 12-LO on EPA. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE.

12(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 12-LO on EPA. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE.