Life Science

A structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.

A structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.

A structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.

A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs.

A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs.

A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs.

A metabolite of 14,15-LTC4 and 14,15-LTD4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine.

A metabolite of 14,15-LTC4 and 14,15-LTD4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine.

A metabolite of 14,15-LTC4 and 14,15-LTD4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency compared LTC4, but approximately 100-fold greater potency than histamine.

Butoconazole is an imidazole derivative that exhibits antifungal/antimycotic and anti-parasitic activities it likely inhibits 14-a demethylase. Butoconazole displays particularly effective antimicrobial activity against species of Candida,

Amorolfine is an antifungal compound that prevents ergosterol synthesis through the inhibition of sterol 14a-demethylase. Amorolfine increases release of prostaglandin D2 metabolites, inhibiting release of thromboxane B2 (TxB2), activation of NF-?B,

Butoconazole is an imidazole derivative that exhibits antifungal/antimycotic and anti-parasitic activities it likely inhibits 14-a demethylase. Butoconazole displays particularly effective antimicrobial activity against species of Candida,