Life Science

15(R)-PGE1 is the &ldquounnatural&rdquo C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC₅₀ of 189 &microM.

15(R)-PGE1 is the &ldquounnatural&rdquo C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC₅₀ of 189 &microM.

15(R)-PGE1 is the &ldquounnatural&rdquo C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC₅₀ of 189 &microM.

15(R)-PGE2 is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays.

15(R)-PGE2 is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays.

15(R)-PGE2 is the C-15 epimer of the naturally occurring 15(S)-PGE2. 15(R)-PGE2 is much less potent than the natural stereoisomer in most biological assays.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(S)-15-methyl PGD2 is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet

15(S)-15-methyl PGE1 is a metabolically stable synthetic analog of PGE1. In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.