Life Science

A prodrug form of 5-azacytidine, an inhibitor of DNA methyltransferaes, that may reverse epigenetic changes.

A prodrug form of 5-azacytidine, an inhibitor of DNA methyltransferaes, that may reverse epigenetic changes.

A prodrug form of 5-azacytidine, an inhibitor of DNA methyltransferaes, that may reverse epigenetic changes.

An in vitro inhibitor of reverse transcriptases from retroviruses, including HIV-1 and visna (Kis = 20 and 37 nM, respectively) also blocks, in vitro, mammalian and bacterial DNA polymerases.

A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.

A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.

A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.

Used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum.

Used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum.

Used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum.

An analog of adenosine used to prepare nucleoside derivatives as inhibitors of viral RNA translation and replication.

An analog of adenosine used to prepare nucleoside derivatives as inhibitors of viral RNA translation and replication.