Life Science

A dihydroxy PUFA and a hydrolysis product of LTA4.

A dihydroxy PUFA and a hydrolysis product of LTA4.

A dihydroxy PUFA and a hydrolysis product of LTA4.

One of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4.

One of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4.

One of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4.

5(S)-HEPE is produced by 5-LO catalyzed oxidation of EPA. While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented.

5(S)-HEPE is produced by 5-LO catalyzed oxidation of EPA. While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented.

5(S)-HEPE is produced by 5-LO catalyzed oxidation of EPA. While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented.

5(S)-HEPE is produced by 5-LO catalyzed oxidation of EPA. While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented.

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (&plusmn)5-HETE lactone to inhibit RBL-1 cell 5-LO (IC₅₀ = 27 &microM) may be

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (&plusmn)5-HETE lactone to inhibit RBL-1 cell 5-LO (IC₅₀ = 27 &microM) may be