Life Science

An inhibitor of DNA methyltransferases that reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.

An inhibitor of DNA methyltransferases that reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.

An inhibitor of DNA methyltransferases that reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.

A building block for use in click chemistry reactions that enables selective conjugation of peptides with various molecules and can be used for the cyclization of peptides.

A building block for use in click chemistry reactions that enables selective conjugation of peptides with various molecules and can be used for the cyclization of peptides.

A building block for use in click chemistry reactions that enables selective conjugation of peptides with various molecules and can be used for the cyclization of peptides.

A thymidine analog used to label DNA newly synthesized during the S phase of the cell cycle.

A thymidine analog used to label DNA newly synthesized during the S phase of the cell cycle.

A thymidine analog used to label DNA newly synthesized during the S phase of the cell cycle.

A thymidine analog used to label DNA newly synthesized during the S phase of the cell cycle.

Selective inhibitor of aldo-keto reductase 1C1 (AKR1C1 Ki = 140 nM) versus AKR1C2 and AKR1C3 (Ki = 1.97 and 21 &microM, respectively) does not inhibit AKR1C4 at 100 &microM.

Selective inhibitor of aldo-keto reductase 1C1 (AKR1C1 Ki = 140 nM) versus AKR1C2 and AKR1C3 (Ki = 1.97 and 21 &microM, respectively) does not inhibit AKR1C4 at 100 &microM.