Life Science

An analog of cAMP that super-activates Epacs (AC₅₀ = 1.8 &microM), dissociating GDP from Rap1 more strongly than the natural Epac agonist, cAMP strongly selective for EPac over PKA.

8-piperazin-1-yl-Isoquinoline (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.

8-piperazin-1-yl-Isoquinoline (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.

8-piperazin-1-yl-Isoquinoline (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.

8-piperazin-1-yl-Isoquinoline (hydrochloride) is a synthetic intermediate useful for pharmaceutical synthesis.

A prenylflavonoid with potent estrogenic activity that inhibits both ER&alpha and ER&beta (IC₅₀s = 57 and 68 nM, respectively) effective in vivo, suppressing bone loss and temperature changes in rat models of osteoporosis and

A prenylflavonoid with potent estrogenic activity that inhibits both ER&alpha and ER&beta (IC₅₀s = 57 and 68 nM, respectively) effective in vivo, suppressing bone loss and temperature changes in rat models of osteoporosis and

A prenylflavonoid with potent estrogenic activity that inhibits both ER&alpha and ER&beta (IC₅₀s = 57 and 68 nM, respectively) effective in vivo, suppressing bone loss and temperature changes in rat models of osteoporosis and

A prenylflavonoid with potent estrogenic activity that inhibits both ER&alpha and ER&beta (IC₅₀s = 57 and 68 nM, respectively) effective in vivo, suppressing bone loss and temperature changes in rat models of osteoporosis and

CLA refers to a family of 8 geometric isomers of linoleic acid in which the two double bonds are contiguous. 9(E),11(E)-CLA is the 9,11 all-trans isomer of linoleic acid.

A certified reference material that is structurally similar to known phytocannabinoids has been found as a byproduct in Cannabis processing potential impurity or degradant in preparations of ?9-THC,,

9(R)-HETE is an enantiomer which makes up 50% of (&plusmn)9-HETE (Item No. 34400). At a concentration of 300 nM, 9(R)-HETE activates RXR&gamma-dependent transcription 1.5 fold relative to a control.