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18317-500A selective inhibitor of SUV420H1 and SUV420H2 (IC<sub>50</sub>s = 25 and 144 nM, respectively) that inhibits the di- and trimethylation of H4K20me in multiple cell lines.
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11016-1A divalent cation ionophore, commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways also used to produce apoptosis through calcium overload, as occurs during hypoxic or
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11016-10A divalent cation ionophore, commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways also used to produce apoptosis through calcium overload, as occurs during hypoxic or
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11016-25A divalent cation ionophore, commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways also used to produce apoptosis through calcium overload, as occurs during hypoxic or
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11016-5A divalent cation ionophore, commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways also used to produce apoptosis through calcium overload, as occurs during hypoxic or
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16081-10A potent, peptide-competitive inhibitor of the lysine methyltransferase G9a (IC<sub>50</sub> = 3.3 nM) significantly reduces the cellular levels of dimethylation on histone 3 at lysine 9 (H3K9Me2) in PC3 cells also blocks the interaction of
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16081-50A potent, peptide-competitive inhibitor of the lysine methyltransferase G9a (IC<sub>50</sub> = 3.3 nM) significantly reduces the cellular levels of dimethylation on histone 3 at lysine 9 (H3K9Me2) in PC3 cells also blocks the interaction of
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18168-1A selective inhibitor of Src family kinases, with IC<sub>50</sub> values for Src, Lck, Lyn, and Hck of 9, 3, 3, and 0.43 nM, respectively induces growth arrest and apoptosis in chronic myelogenous leukemia cell lines prevents differentiation while
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18168-10A selective inhibitor of Src family kinases, with IC<sub>50</sub> values for Src, Lck, Lyn, and Hck of 9, 3, 3, and 0.43 nM, respectively induces growth arrest and apoptosis in chronic myelogenous leukemia cell lines prevents differentiation while
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18168-25A selective inhibitor of Src family kinases, with IC<sub>50</sub> values for Src, Lck, Lyn, and Hck of 9, 3, 3, and 0.43 nM, respectively induces growth arrest and apoptosis in chronic myelogenous leukemia cell lines prevents differentiation while
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18168-5A selective inhibitor of Src family kinases, with IC<sub>50</sub> values for Src, Lck, Lyn, and Hck of 9, 3, 3, and 0.43 nM, respectively induces growth arrest and apoptosis in chronic myelogenous leukemia cell lines prevents differentiation while
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14580-10A competitive antagonist of the nucleotide receptor P2X7 (pIC<sub>50</sub> = 6.9) inhibits both calcium flux and IL-1&beta release mediated by P2X7 while not affecting the activity of other P2X receptors used to evaluate the role of P2X7 in