Life Science

A linear mixed-type inhibitor of nNOS having a Ki value of 2.69 &microM normally present in small quantities in the cerebral cortex of cats with increased levels following seizure.

&alpha-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl protein transferase (FPTase). At concentrations greater than 1 &microM, &alpha-hydroxy farnesyl

&alpha-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl protein transferase (FPTase). At concentrations greater than 1 &microM, &alpha-hydroxy farnesyl

&alpha-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl protein transferase (FPTase). At concentrations greater than 1 &microM, &alpha-hydroxy farnesyl

A reactive metabolite of tamoxifen that is formed by the action of CYP3A4 in human liver can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety.

A reactive metabolite of tamoxifen that is formed by the action of CYP3A4 in human liver can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety.

A reactive metabolite of tamoxifen that is formed by the action of CYP3A4 in human liver can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety.

A reactive metabolite of tamoxifen that is formed by the action of CYP3A4 in human liver can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety.

An &alpha-hydroxy acid, overproduced in 2-hydroxyglutaric aciduria mutations in IDH1 and IDH2 cause these enzymes to convert isocitrate to 2-hydroxyglutarate competitively inhibits &alpha-ketoglutarate-dependent dioxygenases, including lysine

An &alpha-hydroxy acid, overproduced in 2-hydroxyglutaric aciduria mutations in IDH1 and IDH2 cause these enzymes to convert isocitrate to 2-hydroxyglutarate competitively inhibits &alpha-ketoglutarate-dependent dioxygenases, including lysine

An &alpha-hydroxy acid, overproduced in 2-hydroxyglutaric aciduria mutations in IDH1 and IDH2 cause these enzymes to convert isocitrate to 2-hydroxyglutarate competitively inhibits &alpha-ketoglutarate-dependent dioxygenases, including lysine

ALA is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.